Circwhsc1
WebcircWHSC1, miR-532-3p, and latent transforming growth factor-β binding protein 2 (LTBP2) was conrmed by luciferase reporter and biotinylated RNA pull-down assays. A nude mice xenograft tumor model was established to evaluate the anti-tumorigenic role of circWHSC1 silencing in vivo. CircWHSC1 was overexpressed in CaCx tissues and cell lines and its WebMar 2, 2024 · The interplay among circWHSC1, miR-532-3p, and latent transforming growth factor-β binding protein 2 (LTBP2) was confirmed by luciferase reporter and biotinylated …
Circwhsc1
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WebCompared with vector transfected group, subcutaneous injection of circWHSC1-overexpressed cells showed a more rapid rate of growth and larger tumor volume (a, b). The expression of circWHSC1 was ... WebDec 1, 2024 · The role of circWHSC1 in vivo was verified by tumor xenograft assay. The relationship between miR-212-5p and circWHSC1 or AKT3 was verified via dual-luciferase reporter and RNA pull-down assays. CircWHSC1 was upregulated in BC tissues and cells. Also, circWHSC1 could discriminate BC tissues and paracancerous normal tissues.
WebOct 8, 2024 · Exosomal circWHSC1 shifts the morphology of peritoneal mesothelial cells to fibroblast-like and upregulates N-cadherin and MUC1 in peritoneal mesothelial cells. Furthermore, the peritoneal injection of … WebDec 31, 2024 · We found that circWhsc1 was enriched in neonatal mouse hearts, particularly in cardiac ECs, and was further upregulated both in ECs and EC-derived EVs under hypoxic conditions. When cocultured with hypoxia-preconditioned neonatal ECs or their secreted EVs, both neonatal and adult CMs exhibited an increased proliferation rate …
WebCircWHSC1 functioned as the sponge for miR-142-3p, which directly targeted HOXA1. Inhibition of miR-142-3p ameliorated the effects of circWHSC1 knockdown on HCC cell proliferation and metastasis. Moreover, miR-142-3p overexpression restrained the growth and motility of HCC cells, with HOXA1 elevation reversing the impacts. WebMay 7, 2024 · Abstract Circular RNAs (circRNAs) play important roles in human cancer progression. Their high stability and tissue specificity make circRNAs important molecular targets for clinical diagnosis, tre...
WebApr 29, 2024 · The enclosed configuration of circRNAs protects them from degradation and potentiates them as biomarkers. Several circRNAs such as circMUC16, circRNA_MYLK, circRNA-UBAP2, circWHSC1, hsa_circ_0013958, circFGFR3, hsa_circRNA_102958 and circ_0072995 have been found to be up-regulated in this cancer, acting as oncogenes.
WebAug 8, 2024 · 2693 Hilltop Rd, Clermont, FL 34711. 11514 Beaman Cir, Clermont, FL 34711. 10001 Crenshaw Cir, Clermont, FL 34711 is a 3 bedroom, 2 bathroom, 2,074 sqft … bishop elysee youtubeWebCompared with the group transfected with control vector, overexpression of circWHSC1 in CAOV3 increased cell growth (a), reduced cell apoptosis (c), increased cell migration (e) and invasion rate (g). bishop ellis funeralWebJul 27, 2024 · CircWHSC1 is an independent indicator of poor prognosis in NSCLC patients, and functions as a ceRNA of miR-296-3p to up-regulate AKT3, consequently promotes NSCLC cell growth and metastasis. Targeting circWHSC1 might be a prospective strategy for diagnosis, therapeutics, and prognosis of NSCLC. bishop ellis schoolWebOct 30, 2024 · Silence of circWHSC1 exerted the opposite effects. Additionally, circWHSC1 could sponge miR-145 and miR-1182 and up-regulate the expression of downstream targets MUC1 and hTERT. Exosomal circWHSC1 can be transferred to peritoneal mesothelial cells and promotes peritoneal dissemination. Conclusions bishop elyseeWebDec 1, 2024 · CircWHSC1 was a sponge of miR-212-5p in TNBC cells. (A) The subcellular localization of circWHSC1 in TNBC cells was determined by qRT-PCR. (B) The binding … dark history of the easter bunnybishop ellis wifeWebMar 9, 2024 · CircWHSC1 regulates malignancy and glycolysis by the miR-212-5p/AKT3 pathway in triple-negative breast cancer. Inhibition of lncRNA TCONS_00077866 Ameliorates the High Stearic Acid Diet-Induced Mouse Pancreatic beta-Cell Inflammatory Response by Increasing miR-297b-5p to Downregulate SAA3 Expression. dark history of thanksgiving