Cl4-tcr
WebTo dem- onstrate that the tetramers bind the appropriate receptors, LN cells from CL4 TCR transgenic mice were stained. Tetramer-positive cells represented 80% of the transgenic … WebApr 13, 2024 · 现货发售 Claudin家族再添新成员:全长Claudin 4蛋白. 来源: 北京百普赛斯生物科技股份有限公司 2024-4-13 访问量:35 评论 (0) 导读. 转移是指由于癌细胞扩散从原发部位到达其他部位继续生长的过程,也是导致癌症患者的死亡率居高不下的主要原因。. 转移 …
Cl4-tcr
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WebFigure Legend Snippet: (A) CFSE-labeled HA-specific CD8 + CD25 − T cells from CL4-TCR transgenic mice were adoptively transferred into VILLIN-HA and BALB/c recipient mice. At day 4 after adoptive transfer cells from the MLN of recipient mice were isolated and stained for the expression of CD8 and Foxp3. WebJul 1, 2000 · Using CL4-TCR single transgenic mice, in which most CD8+ T cells express a TCR specific for the influenza virus hemagglutinin HA512-520 peptide:Kd complex, we first show that i.v. injection of soluble HA512-520 peptide induces transient activation followed by apoptosis of Tc1-like CD8+ T cells. We next tested a similar tolerance induction ...
WebMay 20, 2024 · The T cell receptor (TCR) of T cells from CL4 TCR transgenic mice recognizes the HA peptide 518 to 526 (IYSTVASSL) as restricted by H2-Kd. Upon … WebCL4-TCR transgenes by polymerase chain reaction (PCR) using specific primers. Mice were bred and maintained under specific pathogen-free conditions and used for experiments at 6 to 18 weeks of age. All animal experi-ments were performed in agreement with local regula-tions.
WebJan 31, 2008 · (referred to as GFAP-HA hereafter). HA peptides are expressed by EGCs and recognized by CD8 T cells that express a T-cell receptor (TCR) specific for K d:HA 512–520 (CL4) or CD4 T cells that … WebAug 1, 2006 · Lymphocytes from the spleen of CL4-TCR and VILLIN-HA × CL4-TCR transgenic mice were isolated and used for in vitro proliferation assays in the presence or …
WebSep 1, 2008 · Section snippets Mice. VILLIN-HA mice express the A/PR8/34 HA from influenza virus A under control of the enterocyte-specific VILLIN promoter as described …
WebDec 1, 2000 · However, it is interesting that CL4-TCR CD8 + cells stimulated with APC and peptide can also lose the CD8 molecule, especially in light of the fact that activation of CL4-TCR-expressing T cells by Ag-pulsed APC or by soluble monomeric MHC-peptide complexes was found to be CD8-dependent (30, 36). Because the decrease in the … tropical smoothie cafe msgWebMay 21, 2024 · The T cell receptor (TCR) of T cells from CL4 TCR transgenic mice recognizes the HA peptide 518 to 526 (IYSTVASSL) as restricted by H2-K d. Upon adoptive transfer into RencaHA tumor-bearing mice, CL4 CTL infiltrate the tumor and acquire a suppressed phenotype ( 7 ). tropical smoothie cafe middletown kyWeb005308 B10.Cg- H2 d Tg(TcraCl4,TcrbCl4)1Shrm/ShrmJ These transgenic mice express a T-cell receptor specific for an epitope of hemagglutinin that is restricted by MHC class I … tropical smoothie cafe minimum wage